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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HIRA
All Species:
30.61
Human Site:
S614
Identified Species:
42.08
UniProt:
P54198
Number Species:
16
Phosphosite Substitution
Charge Score:
-0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P54198
NP_003316.3
1017
111835
S614
L
L
E
S
S
S
D
S
D
E
K
V
P
L
A
Chimpanzee
Pan troglodytes
XP_001165585
1017
111787
S614
L
L
E
S
S
S
D
S
D
E
K
V
P
L
A
Rhesus Macaque
Macaca mulatta
XP_001112873
1138
124408
S735
L
L
E
S
S
S
D
S
D
E
K
V
P
L
A
Dog
Lupus familis
XP_543550
1017
111618
S614
L
L
E
S
S
S
D
S
D
E
K
V
P
V
T
Cat
Felis silvestris
Mouse
Mus musculus
Q61666
1015
111748
S612
E
L
E
S
S
S
D
S
D
E
K
V
H
L
A
Rat
Rattus norvegicus
NP_001129232
1015
111665
S612
E
L
D
S
S
S
D
S
D
E
K
V
H
L
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
P79987
1019
112055
S620
I
L
E
S
S
S
D
S
E
E
K
I
P
A
A
Frog
Xenopus laevis
Q8QFR2
1013
112021
D610
R
V
V
E
S
S
S
D
S
E
E
K
I
P
A
Zebra Danio
Brachydanio rerio
XP_696478
1010
111223
S607
K
D
E
T
S
S
D
S
E
D
K
I
M
N
K
Tiger Blowfish
Takifugu rubipres
O42611
1025
111838
A622
A
T
I
N
K
N
L
A
F
N
K
R
K
P
E
Fruit Fly
Dros. melanogaster
O17468
1047
113397
P632
I
S
M
E
T
G
C
P
V
F
P
A
I
S
L
Honey Bee
Apis mellifera
XP_001122939
838
91355
S453
P
P
S
D
T
M
D
S
S
S
N
R
L
R
T
Nematode Worm
Caenorhab. elegans
Q09589
935
103412
K550
I
E
S
V
R
N
K
K
R
K
V
P
A
T
T
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Q32SG6
964
105548
R579
R
L
S
I
E
H
T
R
S
M
A
P
S
S
L
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LXN4
1051
115544
S635
T
E
I
S
C
K
K
S
G
E
T
L
W
S
D
Baker's Yeast
Sacchar. cerevisiae
P32479
840
93871
N455
L
A
T
N
S
A
S
N
Q
K
D
N
N
D
A
Red Bread Mold
Neurospora crassa
Q7RZI0
1035
112420
R613
V
P
T
P
E
F
L
R
P
A
V
I
S
P
N
Conservation
Percent
Protein Identity:
100
99.9
88.4
96.5
N.A.
95.7
95.5
N.A.
N.A.
86
78
69.8
67.7
31.1
40
26.5
N.A.
Protein Similarity:
100
99.9
88.9
98
N.A.
97.5
97.7
N.A.
N.A.
93.1
88.5
83.2
81.3
48
55.1
46.1
N.A.
P-Site Identity:
100
100
100
86.6
N.A.
86.6
80
N.A.
N.A.
73.3
26.6
40
6.6
0
13.3
0
N.A.
P-Site Similarity:
100
100
100
93.3
N.A.
86.6
86.6
N.A.
N.A.
93.3
40
66.6
26.6
13.3
20
20
N.A.
Percent
Protein Identity:
N.A.
25.6
N.A.
25
22.4
25.9
Protein Similarity:
N.A.
43.7
N.A.
43.3
41.2
45.8
P-Site Identity:
N.A.
6.6
N.A.
20
20
0
P-Site Similarity:
N.A.
6.6
N.A.
26.6
46.6
13.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
6
6
0
0
0
6
0
6
0
6
6
6
6
6
48
% A
% Cys:
0
0
0
0
6
0
6
0
0
0
0
0
0
0
0
% C
% Asp:
0
6
6
6
0
0
53
6
36
6
6
0
0
6
6
% D
% Glu:
12
12
42
12
12
0
0
0
12
53
6
0
0
0
6
% E
% Phe:
0
0
0
0
0
6
0
0
6
6
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
6
0
0
6
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
6
0
0
0
0
0
0
12
0
0
% H
% Ile:
18
0
12
6
0
0
0
0
0
0
0
18
12
0
0
% I
% Lys:
6
0
0
0
6
6
12
6
0
12
53
6
6
0
6
% K
% Leu:
30
48
0
0
0
0
12
0
0
0
0
6
6
30
12
% L
% Met:
0
0
6
0
0
6
0
0
0
6
0
0
6
0
0
% M
% Asn:
0
0
0
12
0
12
0
6
0
6
6
6
6
6
6
% N
% Pro:
6
12
0
6
0
0
0
6
6
0
6
12
30
18
0
% P
% Gln:
0
0
0
0
0
0
0
0
6
0
0
0
0
0
0
% Q
% Arg:
12
0
0
0
6
0
0
12
6
0
0
12
0
6
0
% R
% Ser:
0
6
18
48
59
53
12
59
18
6
0
0
12
18
0
% S
% Thr:
6
6
12
6
12
0
6
0
0
0
6
0
0
6
18
% T
% Val:
6
6
6
6
0
0
0
0
6
0
12
36
0
6
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
6
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _